
NMS Labs launches another unique test suitable for the evaluation of toxicity vs. efficacy, and helping physicians with therapeutic drug monitoring (TDM) of patients for the therapeutic agent, Methotrexate.
Using the highly specific and sensitive technique of LC-MS/MS, this test expands upon the group of chemotherapeutic TDM tests already offered by NMS Labs which includes Busulfan, Mercaptopurine, Mitotane, Platinum, Tamoxifen and metabolites and Exemestane (New!).
Traditional immunoassays used to measure methotrexate are susceptible to interference from the methotrexate metabolite DAMPA. Results obtained from the LC-MS/MS are not subject to this interference and can help ascertain whether a given patient is within a commonly accepted therapeutic range, whether concentrations reflect true increases or decreases in serial collections, and warn of potential toxicities associated with overdosing of the compound.
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