Busulfan, Serum/Plasma Test (0820SP)
| Analysis Code |
0820SP |
| Test Name |
Busulfan, Serum/Plasma |
| Test Includes |
Busulfan [LC-MS/MS] |
| Compound Synonym(s) |
Busulfex®
Myleran® |
| Purpose |
Therapeutic Drug Monitoring; The test is an analytical service for the quantification of busulfan in a specimen. It does not provide an area-under-the-curve (AUC) calculation, busulfan clearance information or a recommendation on adjustment to dosing. |
| Category |
Antineoplastic |
| Method(s) |
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) |
| Specimen Requirements |
2 mL Serum or Plasma |
| Transport Temperature |
Frozen |
| Specimen Container |
Plastic container (preservative-free) |
| Special Handling |
Collect 4 mL of blood in Green top tube (Sodium Heparin).
Blood samples should be placed on wet ice immediately after collection. Centrifuge at 4 degrees Celcius within 1 hour and separate Serum or Plasma into a plastic screw capped vial using approved guidelines. The plasma, harvested into appropriate storage tube should be frozen immediately at -20 degrees Celcius and shipped frozen on dry ice. |
| Light Protection Required |
Not Required |
| Stability |
Room Temperature: Not Stable
Refrigerated: 7 day(s)
Frozen (-20 °C): 30 day(s) |
| Rejection Criteria |
Received Room Temperature. Polymer gel separation tube (SST or PST). |
| Day(s) Test Set-up |
[LC-MS/MS] Monday 2nd Shift 3 days |
| Suggested CPT Code |
[LC-MS/MS] 83789 |
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