Test Summary Sheet for:

Purpose
Therapeutic Drug Monitoring; Compliance Monitoring
Method(s)
Gas Chromatography (GC)
Suggested CPT Code(s)
80375
New York State Approval Status

Approved

Turnaround Time

8 days

Test Includes
1 Diethyldithiocarbamate Disulfiram Metabolite Gas Chromatography (GC) mcg/mL 0.05 Alcohol Deterrent

Test Also Known As
Antabuse; DEDTC; Diethyldithiocarbamate
Specimen Type
Serum or Plasma
Requested Volume
7 mL
Minimum Volume
3.2 mL
Special Handling
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines. Freeze at -70 C upon collection and ship on dry ice. Ship overnight Monday through Thursday, to arrive at NMS Labs the following day.
Specimen Container
Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature
Frozen
Light Protection
Not Required
Rejection Criteria
Glass container. Polymer gel separation tube (SST or PST).

Rejection criteria pertain to clinical specimen submissions only.

Stability
Room Temperature: Undetermined
Refrigerated: Undetermined
Frozen (-20 °C): Not Stable
Frozen (-70 °C): 14 day(s)

Disulfiram is rapidly and completely reduced to diethyldithiocarbamate (DEDTC) in blood within 4 minutes of addition to human blood or plasma. DEDTC, an excellent chelator of numerous metal ions, has an in vitro half-life of approximately 70 minutes in either human blood or plasma at room temperature, but nonenzymatically degraded (especially in an acid medium) to carbon disulfide and diethylamine.

It is required that specimens be frozen at -70°C immediately after being drawn and kept frozen. If the specimens are not kept frozen, this may cause lower or negative result values.
1 Diethyldithiocarbamate Disulfiram Metabolite Gas Chromatography (GC) mcg/mL 0.05 Alcohol Deterrent

Interface Map

LOINC® Information

The CPT Codes provided in this document are based on AMA Guidelines and are for informational purposes only. NMS Labs Does not assume responsibility for billing errors due to Reliance on the CPT Codes listed in this document.

*The information contained in this document represents database configurations, as they will appear on the effective date listed above.