Perfluoroalkyl Substances (PFAS), Serum/Plasma

Purpose

Monitoring for exposure to Per- and Polyfluorinated alkyl substances

Method(s)

High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)

Suggested CPT Code(s)

83921

New York State Approval Status

Approved

Turnaround Time

7 days

Test Includes


1	Perfluorobutanesulfonic Acid (as the linear isomer)	PFBS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
2	Perfluoroheptanoic Acid (as the linear isomer)	PFHpA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
3	Perfluorohexanesulfonic Acid (as the linear isomer)	PFHxS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
4	Perfluorooctanoic Acid (as the linear isomer)	FC-143 Component; PFOA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.5	Environmental/Occupation Toxin
5	Perfluorononanoic Acid (as the linear isomer)	PFNA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
6	Perfluorooctanesulfonic Acid (as the linear isomer)	PFOS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.5	Environmental/Occupation Toxin

Test Also Known As

Pentadecafluorooctanoic Acid

Compliance Statement

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.

Sample Type

Serum or Plasma

Requested Volume

2 mL

Minimum Volume

0.7 mL

Special Handling

Sample collection devices coated with PTFE/Teflon® and PVDF should be avoided because of potential specimen contamination.

Serum: Collect sample in Red top tube

Plasma: Collect sample in Lavender top tube (EDTA).
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines.

Sample Container

Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature

Refrigerated

Light Protection

Not Required

Rejection Criteria

Polymer gel separation tube (SST or PST).

Rejection criteria pertain to clinical sample submissions only.

Stability

Room Temperature: 30 day(s)
Refrigerated: 30 day(s)
Frozen (-20 °C): 1 month(s)


1	Perfluorobutanesulfonic Acid (as the linear isomer)	PFBS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
2	Perfluoroheptanoic Acid (as the linear isomer)	PFHpA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
3	Perfluorohexanesulfonic Acid (as the linear isomer)	PFHxS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
4	Perfluorooctanoic Acid (as the linear isomer)	FC-143 Component; PFOA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.5	Environmental/Occupation Toxin
5	Perfluorononanoic Acid (as the linear isomer)	PFNA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.05	Environmental/Occupation Toxin
6	Perfluorooctanesulfonic Acid (as the linear isomer)	PFOS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.5	Environmental/Occupation Toxin

Example Report (Negative)

Example Report (Positive)

Interface Map

3427SP Perfluoroalkyl Substances (PFAS), Serum/Plasma - Current Version
Analyte	Units	Analyte Mapping Code	LOINC®
Perfluorobutanesulfonic Acid (as the linear isomer)	ng/mL	PFBS
Perfluoroheptanoic Acid (as the linear isomer)	ng/mL	PFHPA
Perfluorohexanesulfonic Acid (as the linear isomer)	ng/mL	PFHXS
Perfluorooctanoic Acid (as the linear isomer)	ng/mL	PFOA	60157-5
Perfluorononanoic Acid (as the linear isomer)	ng/mL	PFNA
Perfluorooctanesulfonic Acid (as the linear isomer)	ng/mL	PFOS

LOINC^® Information

3427SP Perfluoroalkyl Substances (PFAS), Serum/Plasma - Current Version
Analyte	Units	Analyte Mapping Code	LOINC®
Perfluorobutanesulfonic Acid (as the linear isomer)	ng/mL	PFBS
Perfluoroheptanoic Acid (as the linear isomer)	ng/mL	PFHPA
Perfluorohexanesulfonic Acid (as the linear isomer)	ng/mL	PFHXS
Perfluorooctanoic Acid (as the linear isomer)	ng/mL	PFOA	60157-5
Perfluorononanoic Acid (as the linear isomer)	ng/mL	PFNA
Perfluorooctanesulfonic Acid (as the linear isomer)	ng/mL	PFOS

Some LOINC^® codes may not have been assigned or are not available.

This material contains content from LOINC (http://loinc.org). LOINC is copyright ^® 1995-2023, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC^® is a registered United States trademark of Regenstrief Institute, Inc.

The CPT Codes provided in this document are based on AMA Guidelines and are for informational purposes only. NMS Labs Does not assume responsibility for billing errors due to Reliance on the CPT Codes listed in this document.

*The information contained in this document represents database configurations, as they will appear on the effective date listed above.