Perfluoroalkyl Substances (PFAS), Serum/Plasma

Purpose

Monitoring for exposure to Per- and Polyfluorinated alkyl substances

Method(s)

High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)

Suggested CPT Code(s)

83921

New York State Approval Status

Approved

Known Interference(s)

PFHpA [LC-MS/MS]: Perfluorohexanoic Acid (PFPxA); Perfluoropentanoic Acid (PFPeA)

PFNA [LC-MS/MS]: Perfluorodecanoic Acid (PFDA)

Turnaround Time

7-14 days

Test Includes


1	PFBS	Perfluorobutane Sulfonic Acid	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin
2	PFHpA	Perfluoroheptanoic Acid	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin	Perfluorohexanoic Acid (PFPxA); Perfluoropentanoic Acid (PFPeA)
3	Branched PFOA Isomers	Perfluorooctanoic Acid (PFOA) branched isomers; Sb-PFOA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin
4	Linear PFOA Isomer	n-Perfluorooctanoic Acid (PFOA) linear isomer; n-PFOA	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin
5	Total PFOA Isomers	Sum of linear and branched Perfluorooctanoic Acid (PFOA) isomers	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL
6	PFHxS	Perfluorohexane Sulfonic Acid	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin
7	PFNA	Perfluorononanoic Acid	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin	Perfluorodecanoic Acid (PFDA)
8	Branched PFOS Isomers	Perfluoromethylheptane Sulfonic Acid (PFOS) branched isomers; Sm-PFOS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin
9	Linear PFOS Isomer	n-Perfluorooctane Sulfonic Acid (PFOS) linear isomer; n-PFOS	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL	0.1	Environmental/Occupation Toxin
10	Total PFOS Isomers	Sum of linear and branched Perfluorooctane Sulfonic Acid (PFOS) isomers	High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)	ng/mL

Test Also Known As

Pentadecafluorooctanoic Acid

Compliance Statement

This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.

Sample Type

Serum or Plasma

Requested Volume

1 mL

Minimum Volume

0.3 mL

Special Handling

Sample collection devices coated with PTFE/Teflon® and PVDF should be avoided because of potential specimen contamination.

Serum: Collect sample in Red top tube

Plasma: Collect sample in Lavender top tube (EDTA).
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines.

Sample Container

Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature

Refrigerated

Light Protection

Not Required

Rejection Criteria

Polymer gel separation tube (SST or PST).

Rejection criteria pertain to clinical sample submissions only.

Stability

Room Temperature: 17 day(s)
Refrigerated: 17 day(s)
Frozen (-20 °C): 3 month(s)

The CPT Codes provided in this document are based on AMA Guidelines and are for informational purposes only. NMS Labs Does not assume responsibility for billing errors due to Reliance on the CPT Codes listed in this document.

*The information contained in this document represents database configurations, as they will appear on the effective date listed above.