Test Code 3427SP

Test Name Perfluoroalkyl Substances (PFAS), Serum/Plasma

Test has pending updates: 04/04/2022

Purpose
Monitoring for exposure to Per- and Polyfluorinated alkyl substances
Method(s)
High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)
Suggested CPT Code(s)
83921
New York State Approval Status

Approved

Known Interference(s)
Perfluoroheptanoic Acid (as the linear isomer) [LC-MS/MS]: Perfluorohexanoic Acid (PFPxA); Perfluoropentanoic Acid (PFPeA)
Perfluorononanoic Acid (as the linear isomer) [LC-MS/MS]: Perfluorodecanoic Acid (PFDA)
Turnaround Time

7 days

Test Includes
1 Perfluorobutanesulfonic Acid (as the linear isomer) PFBS High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin
2 Perfluoroheptanoic Acid (as the linear isomer) PFHpA High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin Perfluorohexanoic Acid (PFPxA); Perfluoropentanoic Acid (PFPeA)
3 Perfluorohexanesulfonic Acid (as the linear isomer) PFHxS High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin
4 Perfluorooctanoic Acid (as the linear isomer) FC-143 Component; PFOA High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.5 Environmental/Occupation Toxin
5 Perfluorononanoic Acid (as the linear isomer) PFNA High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin Perfluorodecanoic Acid (PFDA)
6 Perfluorooctanesulfonic Acid (as the linear isomer) PFOS High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.5 Environmental/Occupation Toxin

Test Also Known As
Pentadecafluorooctanoic Acid
Compliance Statement
This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.
Specimen Type
Serum or Plasma
Requested Volume
1 mL
Minimum Volume
0.4 mL
Special Handling
Sample collection devices coated with PTFE/Teflon® and PVDF should be avoided because of potential specimen contamination.
Serum: Collect sample in Red top tube
Plasma: Collect sample in Lavender top tube (EDTA).
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines.
Specimen Container
Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature
Refrigerated
Light Protection
Not Required
Rejection Criteria
Polymer gel separation tube (SST or PST).

Rejection criteria pertain to clinical specimen submissions only.

Stability
Room Temperature: 30 day(s)
Refrigerated: 30 day(s)
Frozen (-20 °C): 1 month(s)
1 Perfluorobutanesulfonic Acid (as the linear isomer) PFBS High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin
2 Perfluoroheptanoic Acid (as the linear isomer) PFHpA High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin Perfluorohexanoic Acid (PFPxA); Perfluoropentanoic Acid (PFPeA)
3 Perfluorohexanesulfonic Acid (as the linear isomer) PFHxS High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin
4 Perfluorooctanoic Acid (as the linear isomer) FC-143 Component; PFOA High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.5 Environmental/Occupation Toxin
5 Perfluorononanoic Acid (as the linear isomer) PFNA High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 Environmental/Occupation Toxin Perfluorodecanoic Acid (PFDA)
6 Perfluorooctanesulfonic Acid (as the linear isomer) PFOS High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.5 Environmental/Occupation Toxin

Interface Map

LOINC® Information

The CPT Codes provided in this document are based on AMA Guidelines and are for informational purposes only. NMS Labs Does not assume responsibility for billing errors due to Reliance on the CPT Codes listed in this document.

*The information contained in this document represents database configurations, as they will appear on the effective date listed above.